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In clear contrast, when we compared the Sun spa massage Oceanside of octogenarians vs young, using the same selection criteria as for centenarians, we found that 50 small non-coding RNAs were down-regulated and only one miRNA was up-regulated.

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PLoS One 4, e Grillari, J. Finally, the selected small non-coding RNAs were imported into Pathway Studio v8 Ariadne software to classify the molecular function and biological processes represented by the miRNAs differentially expressed between centenarian and young samples.

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